Impact of Chronic Rhinosinusitis on the Index of Ciliary Beat Efficiency Using Fluorescent Nanosticks: (R-IMPAC)

Launched by CENTRE HOSPITALIER INTERCOMMUNAL CRETEIL · Dec 5, 2019

Keywords

ClinConnect Summary

The R-IMPAC trial is studying how chronic rhinosinusitis (CRS), a condition that causes long-term inflammation in the nasal and sinus areas, affects the movement of tiny hair-like structures called cilia. These cilia help keep our airways clear by moving mucus and particles out of the nose and sinuses. The researchers will use special fluorescent nanosticks to measure how well the cilia are working in patients with CRS who may need surgery to relieve their symptoms.

To be part of this study, participants should be at least 18 years old and have chronic rhinosinusitis that requires surgery or have other nasal issues that need surgical treatment. It's important that they can understand and speak French, and they should not be pregnant or breastfeeding. Those who choose to participate will need to sign a consent form to confirm their agreement. Since the trial has not started recruiting yet, interested individuals can keep an eye out for updates on how to join once it begins.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient ≥ 18 years old
• • Having chronic rhinosinusitis (RCS) requiring surgical treatment. Or
• • With an indication for endonasal surgery for nasal obstruction (turbinoplasty and septoplasty) or for an endonasal surgical approach
• • 2. Acceptance to participate in the protocol with signed informed consent
• • 3. Affiliated or beneficiary of a social security scheme
• Exclusion Criteria:
• • 1. Refusal to participate in the study
• • 2. No one who does not speak or understand French
• • 3. Pregnant or breastfeeding woman
• • 4. Persons who are incapable of reaching the age of majority, under guardianship, guardianship or protection of justice.
• • 5. Simulated participation in another intervention research