IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding

Launched by THOMAS JEFFERSON UNIVERSITY · Dec 18, 2019

Keywords

ClinConnect Summary

This clinical trial is studying two different ways to treat anemia, which is a condition where you don't have enough healthy red blood cells. The researchers want to see if giving iron through an IV (intravenous iron) is more effective than taking iron pills for women who have heavy menstrual bleeding and low iron levels. Women aged 18 to 50 who experience heavy periods and have anemia (a hemoglobin level below 11.5 g/dL) may be eligible to participate.

If you join the study, you will be randomly assigned to receive either the IV iron or the oral iron pills. The researchers will monitor how quickly your anemia improves and will also ask you about your experience with the treatment to see which method you prefer. This trial is important because it could help determine the best way to treat anemia in women dealing with heavy menstrual bleeding.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women aged 18-50.
• • Heavy menstrual bleeding, defined as self-report of bothersome periods with subjectively heavy flow or frequency greater than 7 bleeding days per month.
• • Anemia with hgb \<11.5 g/dL
• Exclusion Criteria:
• • Suspected/confirmed malignancy
• • Severe anemia currently requiring transfusion or emergent operative intervention
• • Allergy or contraindication to either study drug
• • Known iron overload
• • Known sickle cell disease