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Search / Trial NCT04209322

Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation

Launched by UNIVERSITY OF ROMA LA SAPIENZA · Dec 19, 2019

Trial Information

Current as of April 30, 2025

Completed

Keywords

Sciatica Lumbar Disc Herniation Radiofrequency Non Invasive Treatment

ClinConnect Summary

The investigators conducted a multicenter, prospective, randomized trial among patients with at least 6 weeks of sciatic pain to determine whether a strategy of PRF in addition to TFESI leads to better outcomes during the first year than does a strategy of TFESI only means for sciatica treatment.

Eligible patients were 18 to 75 years of age, had a radiologically confirmed disk herniation, and had received a diagnosis from an attending neurologist of an incapacitating lumbosacral radicular syndrome that had lasted for at least 12 weeks. Correlation of magnetic resonance imaging (MRI) findin...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Eligible patients had radiologically confirmed disk herniation, and had received a diagnosis from an attending neurologist of an incapacitating lumbosacral radicular syndrome that had lasted for at least 12 weeks. Correlation of magnetic resonance imaging (MRI) findings with symptoms was required.
  • The occurrence of another episode of symptoms similar to those of the current episode during the previous 12 months were not considered contraindications
  • Exclusion Criteria:
  • Patients presenting with previous spine surgery, spondylolisthesis, cauda equina syndrome, muscle paralysis, or insufficient strength to move against gravity were excluded.
  • Vertebral canal stenosis
  • Other exclusion criteria were cardiac pace-maker implant, pregnancy, or severe coexisting disease.

About University Of Roma La Sapienza

The University of Roma La Sapienza, one of Italy's premier research institutions, is dedicated to advancing medical science and improving patient outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university harnesses its extensive expertise in diverse fields, including medicine, biotechnology, and public health, to conduct rigorous and ethically sound research. Committed to fostering educational excellence and promoting groundbreaking discoveries, La Sapienza actively engages in clinical trials that aim to address critical health challenges and contribute to the development of new therapeutic interventions.

Locations

Rome, , Italy

Aprilia, Lt, Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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