Preoperative Paravertebral Block in Cancer Surgery of the Lung

Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Dec 19, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a method to help manage pain for patients undergoing lung cancer surgery. Researchers want to see if giving a special type of pain relief injection, called a paravertebral block (PVB), before surgery can reduce pain after the operation, lower the need for strong pain medications, and improve recovery. This trial focuses on patients who are having a specific type of lung surgery called video-assisted thoracoscopic surgery (VATS) for removing a part of the lung.

To be eligible for this trial, participants must be at least 18 years old and scheduled for a single lobectomy, which is a type of lung surgery. They should be in generally good health (ASA I-III) and not have any allergies to local anesthetics or opioids. Participants will receive both the pre-surgery and post-surgery injections and will be monitored for their pain levels and recovery experience. It's important for potential participants to know that those with certain medical conditions or previous surgeries may not be suitable for this study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Elective radical primary lung cancer VATS surgery for single lobectomy
• • American Society of Anesthesiology (ASA) I-III
• • Age ≥18
• Exclusion Criteria:
• • Planned open thoracotomy, wedge resection, bilobectomy, pneumonectomy, chest wall resection or total pleurectomy
• • Local anaesthetic or opioid allergy
• • Coagulation disorders
• • Inability to comply with study questionnaire completion
• • Pre-existing pain in chest area or pre-existing pain conditions
• • Local infection/tumour at proposed PVB site
• • Previous lung surgery
• • Planned surgery within 3 months of the primary lung resection