Stratifying Endometrial Cancer Patients Using a PET/MRI Prognostic Model

Launched by IRCCS SAN RAFFAELE · Dec 25, 2019

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help doctors predict how well a patient with endometrial cancer (a type of cancer that affects the lining of the uterus) might respond to treatment before they have surgery. The researchers will use a special imaging technique called PET/MRI, which combines two types of scans, to gather important information about the cancer. This information could help create a non-invasive model to understand the prognosis or outlook for patients, which means they can get a better idea of what to expect.

To participate in this study, you need to be over 18 years old and have been diagnosed with endometrial cancer confirmed by a doctor. You should be in good enough health to undergo surgery and have no issues that would prevent you from having the required imaging tests. If you decide to join the trial, you’ll have imaging done to help gather the necessary data, and your participation will contribute to improving future care for patients with this type of cancer. The study is currently recruiting female participants, and signing an informed consent is required.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • histopathological confirmation of a primary endometrial cancer
• • age \> 18 years
• • no contraindication to surgery (comorbidity, contraindication or lack of consent)
• • no contraindication to preoperative imaging
• • visible tumor at imaging
• • signed inform consent.
• Exclusion Criteria:
• • patients unsuitable for surgical intervention (comorbidity, contraindication or lack of consent, poor performance status)
• • age \< 18 years, c) inability to complete the needed imaging examination (ie, severe claustrophobia)
• • any additional medical condition that may significantly interfere with study compliance
• • all the contraindication for MRI (ie, pacemaker).