EsophaCap for the Detection of Early Esophageal Carcinoma

Launched by JOHNS HOPKINS UNIVERSITY · Dec 26, 2019

Keywords

ClinConnect Summary

This clinical trial, called EsophaCap, is focused on finding new ways to detect early signs of esophageal cancer and Barrett's Esophagus, which can lead to cancer. The researchers aim to identify specific markers in the body that could help catch these conditions early, making treatment more effective. They are currently looking for participants who are scheduled for a specific type of endoscopy (a procedure to examine the esophagus) at Johns Hopkins Hospital between 2016 and 2025.

To be eligible for this study, participants must be over 18 years old and able to swallow a small capsule used for testing. However, individuals with certain conditions, such as having other cancers, previous surgeries on the esophagus, or problems that prevent swallowing the capsule, cannot participate. If you join the study, you can expect to undergo the usual endoscopy procedure along with the new testing method being studied. This trial is a promising step towards improving early detection of esophageal and gastric cancers, which can significantly impact treatment outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025
• • Age greater than 18 years
• • Patients must be able to swallow a capsule
• Exclusion Criteria:
• • Patients in either arm with extra-esophageal malignancies including head and neck and gastric cancer
• • Patients who have undergone esophagectomy
• • Patients who have undergone radiation to the chest
• • Patients who are younger than 18
• • Patients with esophageal stents
• • Patients with esophageal strictures disabling passage of the capsule