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Search / Trial NCT04217226

Perfusion Index-derived Parameters as Predictors Post-induction Hypotension.

Launched by CAIRO UNIVERSITY · Jan 2, 2020

Trial Information

Current as of August 19, 2025

Completed

Keywords

ClinConnect Summary

The perfusion index (PI) is a numerical value for the ratio between pulsatile and non-pulsatile blood flow measured by a special pulse oximeter. PI represents the baseline sympathetic tone which is assumed one of the factors contributing for hypotension. Patients with low PI were reported by Mahendale and Rajasekhar to show greater hypotension after induction of anesthesia. This was explained by the high sympathetic tone in these patients which is suddenly masked by propofol administration leading to profound hypotension. Moreover, The PI has been described as a reliable tool for vascular t...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Adult patients (18-59 years)
  • ASA I-II
  • Patients scheduled for elective surgeries under general anaesthesia
  • Exclusion Criteria:
  • • Operations which will last for less than 15 minutes.
  • Patients with cardiac morbidities (impaired contractility with ejection fraction \< 40% and tight valvular lesions, unstable angina).
  • Patients with heart block and arrhythmia (atrial fibrillation and frequent ventricular or supraventricular premature beat).
  • Patient with decompansted respiratory disease (poor functional capacity, generalized wheezes, peripheral O2 saturation \< 90% on room air).
  • Patients with peripheral vascular disease or long standing DM affecting PVI readings.
  • Pregnancy.

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Bassant abdelhamid, M.D.

Principal Investigator

Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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