Perfusion Index-derived Parameters as Predictors Post-induction Hypotension.
Launched by CAIRO UNIVERSITY · Jan 2, 2020
Trial Information
Current as of August 19, 2025
Completed
Keywords
ClinConnect Summary
The perfusion index (PI) is a numerical value for the ratio between pulsatile and non-pulsatile blood flow measured by a special pulse oximeter. PI represents the baseline sympathetic tone which is assumed one of the factors contributing for hypotension. Patients with low PI were reported by Mahendale and Rajasekhar to show greater hypotension after induction of anesthesia. This was explained by the high sympathetic tone in these patients which is suddenly masked by propofol administration leading to profound hypotension. Moreover, The PI has been described as a reliable tool for vascular t...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • Adult patients (18-59 years)
- • ASA I-II
- • Patients scheduled for elective surgeries under general anaesthesia
- Exclusion Criteria:
- • • Operations which will last for less than 15 minutes.
- • Patients with cardiac morbidities (impaired contractility with ejection fraction \< 40% and tight valvular lesions, unstable angina).
- • Patients with heart block and arrhythmia (atrial fibrillation and frequent ventricular or supraventricular premature beat).
- • Patient with decompansted respiratory disease (poor functional capacity, generalized wheezes, peripheral O2 saturation \< 90% on room air).
- • Patients with peripheral vascular disease or long standing DM affecting PVI readings.
- • Pregnancy.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Bassant abdelhamid, M.D.
Principal Investigator
Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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