Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

Launched by CHINA NATIONAL CENTER FOR CARDIOVASCULAR DISEASES · Jan 5, 2020

Keywords

ClinConnect Summary

This clinical trial is exploring the effects of two surgical techniques—removing a small pouch in the heart called the left atrial appendage and cutting a band of tissue known as the Marshall ligament—during a heart surgery called off-pump coronary artery bypass. The goal is to see if these procedures can help lower the chances of patients developing new atrial fibrillation (a common heart rhythm problem) and having a stroke after their surgery. Atrial fibrillation can increase the risk of stroke and other complications, so understanding the benefits of these techniques is important.

To be part of this study, participants need to be undergoing their first isolated off-pump coronary artery bypass surgery and must not have had any previous heart surgeries or current issues with atrial fibrillation. The trial is currently recruiting patients between the ages of 65 and 74. If eligible, participants can expect to undergo the surgery with these additional procedures and will be monitored for their heart health and any complications following the surgery. This research will help doctors better understand the potential benefits of these techniques in improving patient outcomes after heart surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • isolated first off-pump coronary artery bypass
• Exclusion Criteria:
• • Preoperative atrial fibrillation or a history of atrial fibrillation;
• • Concurrent cardiac or non-cardiac surgery
• • Intraoperative convert to bypass bypass surgery
• • Emergency surgery
• • History of previous cardiac surgery
• • Severe organ dysfunction