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Search / Trial NCT04244604

Vascular Effects of Acute Sodium (VEAS) Study

Launched by INDIANA UNIVERSITY · Jan 24, 2020

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Blood Pressure Racial Disparities Cardiovascular Health Physical Fitness Sleep Dietary Sodium Dietary Salt Diet

ClinConnect Summary

This clinical trial is studying how dietary salt affects blood pressure and blood vessel function in Black and white individuals. Researchers want to understand why Black individuals are more likely to experience high blood pressure when consuming a lot of salt. By looking at how different lifestyles, like sleep, exercise, and nutrition, might play a role, the study aims to uncover important information about cardiovascular health and racial differences.

To participate in this trial, you need to be between 19 and 75 years old, have a blood pressure lower than 150/90 mmHg, and a healthy body weight (with a BMI below 35). You should also be generally healthy, without any serious medical conditions like diabetes or heart disease. Participants can expect to provide some health information, take part in exercises, and possibly give blood for testing. This study is currently looking for volunteers, and your involvement could help improve our understanding of blood pressure and health differences among different racial groups.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Are between the ages of 19-75.
  • 2. Have blood pressure no higher than 150/90 mmHg.
  • 3. Have a BMI below 35 Kg/m2 (otherwise healthy)
  • 4. Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD \& cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular).
  • 5. Do not have any precluding medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) or giving blood (e.g., blood thinners).
  • 6. Are not currently smoking, using smokeless tobacco, nor smoked within the past 12 months.
  • Exclusion Criteria:
  • 1. High blood pressure - greater the 150/90 mmHg
  • 2. Low blood pressure - less than 90/50 mmHg
  • 3. History of cardiovascular disease
  • 4. History of cancer
  • 5. History of diabetes
  • 6. History of kidney disease
  • 7. Obesity (BMI \> 30 kg/m2)
  • 8. Smoking or tobacco use
  • 9. Current pregnancy
  • 10. Nursing mothers
  • 11. Communication barriers

About Indiana University

Indiana University, a leading research institution, is committed to advancing healthcare through innovative clinical trials and rigorous scientific inquiry. With a focus on improving patient outcomes, the university conducts a wide range of studies across various medical disciplines, leveraging its extensive resources and collaborative networks. Indiana University's dedication to ethical research practices and community engagement ensures that its clinical trials not only contribute to scientific knowledge but also prioritize participant safety and well-being. Through its commitment to excellence, Indiana University plays a pivotal role in shaping the future of medicine and enhancing public health.

Locations

Auburn, Alabama, United States

Bloomington, Indiana, United States

Auburn, Alabama, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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