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Search / Trial NCT04249336

Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH

Launched by DOW UNIVERSITY OF HEALTH SCIENCES · Jan 29, 2020

Trial Information

Current as of May 21, 2025

Completed

Keywords

Dentine Hypersensitivity Dentine Sensitivity Oral Dentifrices Bio Active Glasses

ClinConnect Summary

It is a randomized controlled clinical trial with non invasive topical intervention in 140 adult patients of 18 to 60 years age, that will be selected randomly after screening and diagnosis of dentin hypersensitivity, in dental Out Patient Department of Periodontology. Written informed consent will be obtained. Participants will be allocated randomly into four equal study arms for parallel treatment assignment with dentifrices named BioMin F, Colgate Sensitive Pro-Relief Trade Mark,Sensodyne rapid action Trade Mark and Colgate Total Trade Mark dentifrices. Colgate total Trade Mark dentifric...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subjects with at least two teeth sensitive to cold, touch and air blow stimulus
  • Sensitive teeth anterior to molars either due to erosions or abrasions with or without associated gingival recession
  • Teeth with Linear Visual Analogue Scale (VAS) score of ≥ 4 and code 2 of Schiff Cold Air Sensitivity Scale on screening.
  • Exclusion Criteria:
  • Subjects with worst pain response at 100mm on VAS.(Visual Analog Scale)
  • Teeth with orthodontic or prosthetic appliances, Caries, restorations or cracks
  • Localized or generalized gingivitis or pulpitis with heavy calculus
  • Periodontal surgery in the preceding three months
  • Patients using any desensitizing tooth paste or mouth wash up to six weeks before study and taking drugs like anti-inflammatory, sedatives, tranquilizers, analgesics in routine.
  • Pregnant or breastfeeding females.

About Dow University Of Health Sciences

Dow University of Health Sciences (DUHS) is a premier educational and research institution based in Karachi, Pakistan, dedicated to advancing healthcare through innovative research and clinical excellence. As a clinical trial sponsor, DUHS integrates cutting-edge scientific inquiry with practical applications, fostering a collaborative environment that promotes the development of new treatments and therapies. The institution is committed to upholding the highest ethical standards in research, ensuring participant safety, and contributing to the global body of medical knowledge. With a focus on interdisciplinary collaboration and community health impact, DUHS plays a pivotal role in enhancing the quality of healthcare both locally and internationally.

Locations

Karachi, Sindh, Pakistan

Patients applied

0 patients applied

Trial Officials

Syed Jaffar Abbas Zaidi

Study Director

Dow University of Health Sciences

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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