Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Patients.
Launched by YAOUNDE CENTRAL HOSPITAL · Jan 31, 2020
Trial Information
Current as of June 27, 2025
Completed
Keywords
ClinConnect Summary
Aim: to determine and compare the short term effect of angiotensin converting in the management of hypertension as well as the oxidative effect of Zofenopril and perindopril in blacks hypertensive patients in the Yaoundé Central Hospital.
Method: A double-arm, double-blind, randomized and parallel clinical trial conducted at the Yaoundé Central Hospital. Hypertensive patients who are not taking angiotensin-converting enzyme inhibitor or angiotensin receptors blockers, are randomize into 2 groups. Depending on the group, the intervention consisted of the administration of Perindopril 10 mg ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Hypertensive patients
- • On a stable atihypertensive therapies (determined by the investigator) for at least 3 months with no classes changes. The pharmacological treatment should not include an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker
- • Subject must not present any contraindication to exercise
- • Before any study-specific procedure, the appropriate written informed consent must be obtained.
- Exclusion Criteria:
- • Side effects affecting life quality of patients (determined by the Data Safety Monitoring Board).
- • Withdrawal of consent
About Yaounde Central Hospital
Yaoundé Central Hospital is a leading medical institution in Cameroon, dedicated to advancing healthcare through innovative clinical research and patient care. As a prominent sponsor of clinical trials, the hospital is committed to enhancing medical knowledge and improving treatment options across various health conditions. With a multidisciplinary team of experienced healthcare professionals and researchers, Yaoundé Central Hospital fosters a collaborative environment that prioritizes patient safety and ethical standards. The institution plays a vital role in addressing local and global health challenges, contributing to the development of effective therapies and interventions that benefit diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Yaounde, , Cameroon
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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