Adipose Inflammation and Diabetes (FAB)

Launched by GÖTEBORG UNIVERSITY · Feb 3, 2020

Keywords

ClinConnect Summary

The FAB trial is looking into how certain molecules can help reduce inflammation and improve insulin sensitivity in people who are obese. The study will use samples from individuals who have previously undergone gastric bypass surgery to see if these molecules can make a difference in their body’s responses. Researchers want to understand if the effects vary based on each person's unique characteristics.

To participate in this trial, you should be between 18 and 75 years old, have a body mass index (BMI) between 30 and 40, and have had stable weight for at least six months after your gastric bypass surgery, which should have been done over two years ago. You also need to be a non-smoker for at least six weeks before the study. If you join, you’ll be contributing to important research that could help improve treatments for obesity-related conditions. It's important to note that participants need to understand Swedish and should not have any severe medical issues that could affect their ability to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • BMI 30-40 kg/m2
• • Ptos (i.e. excess skin) \> 3 cm
• • Patient underwent gastric bypass surgery \>2 years ago
• • Patient has had a stable weight ≥6 months at the time of operation
• • Patient does not smoke (min 6 weeks prior to surgery)
• Exclusion Criteria:
• • Patients who do not understand spoken and written Swedish
• • American Society of Anesthesiologists (ASA) classification ≥ 3
• • Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
• • Preoperatively known hernia requiring surgical operation
• • Severe mental illness