Cardiometabolic Health and Inflammatory Resolution

Launched by GÖTEBORG UNIVERSITY · Feb 3, 2020

Keywords

ClinConnect Summary

This clinical trial, titled "Cardiometabolic Health and Inflammatory Resolution," is looking to understand how the body's ability to resolve inflammation affects heart and metabolic health in different groups of people based on their weight. They are inviting volunteers who are lean, overweight, or obese to participate in this important research. To join, participants need to be at least 18 years old and have a body mass index (BMI) higher than 18.5. However, certain individuals, like those on multiple medications or with specific health conditions, may not be eligible.

Participants in this trial can expect to go through assessments that will help researchers learn how inflammation affects their health. They will be asked to provide informed consent, meaning they understand what the study involves. It's important for volunteers to be in good health and not have any chronic inflammation or use certain medications that could interfere with the study. This research aims to provide insights that could help improve health outcomes for people with various weight categories.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Informed signed consent has been obtained from the volunteer.
• • The volunteer has a BMI greater than 18.5 kg/m2
• Exclusion Criteria:
• • The study staff contacting a potential participant perceives that the individual has difficulty understanding the information.
• • An MD determines that the individual is on too many medications to participate
• • The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw.
• • The individual is younger than 18 years (relevant for the FAINT-1 and FAINT-2 cohorts)
• • The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication.
• • The individual has some form of chronic inflammation.
• • The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin).
• • The individual uses immunosuppressive drugs (eg, methotrexate).
• • The individual regularly consumes fish oils (omega 3).
• • The individual has significant gastrointestinal problems.
• • The individual smokes or uses chewing tobacco.
• • The individual has been drinking alcohol two days before the study visit.
• • The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination.
• • The individual does not follow instructions given in the research study.