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Search / Trial NCT04257747

Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Feb 4, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Vascularized Composite Allotransplantation Hand Allotransplantation Radial Forearm Flap Magnetic Resonance Imaging Flow Mri Radial Artery Ulnar Artery

ClinConnect Summary

This clinical trial is studying how blood flows through the arteries in the hand, specifically looking at the radial (thumb side), ulnar (pinky side), and interdigital (between the fingers) arteries. The researchers want to understand blood flow in both healthy individuals and those who have had surgery on their hand, like a hand transplant or a radial forearm flap reconstruction. By using a special type of MRI (a medical imaging technique), they hope to find better ways to monitor blood flow, which is crucial for the health of transplanted tissues.

To participate in this study, you need to be an adult (18 years or older) and either a healthy volunteer or a patient who has had a hand transplant or needs specific surgery on the hand. It's important that you do not have any conditions that would prevent you from having an MRI, and you should be able to provide informed consent, meaning you understand the study and agree to take part. If you join the trial, you can expect to undergo MRI scans that will help the researchers gather valuable information about blood flow in the hand, which could improve treatments for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult (≥ 18 years old)
  • patients who has received appropriate information and provided informed consent
  • patients benefiting from social security insurance
  • patients with no contraindications to magnetic resonance imaging
  • healthy volunteer or patient requiring radial forearm flap reconstruction or having received hand allotransplantation.
  • Exclusion Criteria:
  • Person with a contraindication to MRI
  • pregnant or breastfeeding woman
  • minors (\< 18 years)
  • person under guardianship or deprived of liberty by a judicial or administrative decision
  • person with upper limb arteriopathy with the exception of the hand transplant patients group.

About Centre Hospitalier Universitaire, Amiens

The Centre Hospitalier Universitaire (CHU) Amiens is a leading academic medical center in France dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on multidisciplinary collaboration, CHU Amiens integrates patient care, education, and research to enhance treatment outcomes and improve patient quality of life. The institution is committed to ethical standards and regulatory compliance in its clinical research endeavors, aiming to contribute significantly to the medical community and the development of new therapeutic approaches. By fostering partnerships with various stakeholders, CHU Amiens strives to translate scientific discoveries into practical applications that benefit patients and healthcare systems alike.

Locations

Amiens, , France

Patients applied

0 patients applied

Trial Officials

Stéphanie Dakpe, MD

Principal Investigator

CHU Amiens

Jérémie Bettoni, MD

Principal Investigator

CHU Amiens

Olivier Baledent, MD

Principal Investigator

CHU Amiens

Marie-Antoinette Sevestre-Pietri, Pr

Principal Investigator

CHU Amiens

Emmanuel Morelon, Pr

Principal Investigator

Hopital Edouard Herriot

Palmira Petruzzo, MD

Principal Investigator

Hopital Edouard Herriot

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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