Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · Feb 14, 2020

Keywords

ClinConnect Summary

**Clinical Trial Summary: Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy**

This clinical trial is examining whether a special type of local anesthetic called liposomal bupivacaine can help reduce the amount of pain medication needed after an open myomectomy, a surgery to remove fibroids from the uterus. Participants in the study will be randomly assigned to receive either liposomal bupivacaine or a standard version of bupivacaine during their surgery. The main goal of the study is to see how these two types of anesthetics compare in terms of reducing the need for stronger pain medications, known as opioids, after the procedure.

To be eligible for this trial, participants must be women aged between 18 and 75, weigh over 50 kg, and not be pregnant. They should not have any history of allergic reactions to the medications being studied, nor should they have certain medical conditions like serious heart problems or epilepsy. Additionally, participants should not have a history of drug or alcohol abuse or liver disease. If you qualify and join the study, you can expect to receive either type of anesthetic during your surgery and help researchers understand how these treatments impact pain management post-surgery. Your participation could contribute to improving care for future patients undergoing similar procedures.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Not pregnant
• • Weight over 50kg presenting for open myomectomy
• • No history of allergy to any study medication
• • No history of malignant ventricular dysrhythmia, epilepsy, seizure disorder, or chronic pain syndrome other than pain from myomas
• • No history of drug or alcohol use or abuse disorder or pre-existing liver disease.