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Search / Trial NCT04273256

Myo-inositol for the Management of Poor Ovarian Responders: A Prospective Randomized Controlled Trial

Launched by AMERICAN UNIVERSITY OF BEIRUT MEDICAL CENTER · Feb 14, 2020

Trial Information

Current as of June 25, 2025

Unknown status

Keywords

Myo Inositol, In Vitro Fertilization, Poor Ovarian Responders, Infertility

ClinConnect Summary

The management of poor ovarian responders (POR) remains the most challenging in In-Vitro Fertilization (IVF). The incidence of POR ranges between 9 and 24% (Caprio F, et al, 2015).

POR refers to a reduction in the quantity of primordial follicle pool in reproductive age group (Jirge, P. R., 2016, Sunkara, S. K., et al, 2014), in addition to a higher risk of implantation failure (Kailasam C, et al, 2004).

To overcome this condition, adjuvant fertility treatments using controlled ovarian stimulation along with IVF is needed to achieve pregnancy. Despite the use of various treatments includi...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Age: 18-44 years at the time of interview
  • POR patients defined as: AMH\<1.5 ng/nl, AFC of 7 or less, 5 oocytes or less retrieved in a previous cycle
  • * Patients undergoing controlled ovarian stimulation for any indication:
  • Male factor
  • Female factor
  • Exclusion Criteria:
  • Patients with diabetes, thyroid dysfunction
  • Patients with abnormal uterine cavity

About American University Of Beirut Medical Center

The American University of Beirut Medical Center (AUBMC) is a leading academic medical institution in the Middle East, dedicated to advancing healthcare through innovative research, education, and clinical excellence. As a prominent sponsor of clinical trials, AUBMC integrates cutting-edge scientific inquiry with patient-centered care to enhance therapeutic options and improve health outcomes. With a commitment to ethical standards and regulatory compliance, AUBMC collaborates with multidisciplinary teams to conduct rigorous trials that contribute to the global medical knowledge base and address critical health challenges in the region and beyond.

Locations

Beirut, , Lebanon

Patients applied

0 patients applied

Trial Officials

Antoine Abu Mussa, MD

Principal Investigator

American University of Beirut Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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