Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery

Launched by STEEN HVITFELDT POULSEN · Feb 18, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the presence of a condition called wild-type transthyretin amyloidosis (wtATTR-CM) in older patients who are undergoing carpal tunnel release surgery. The researchers want to find out how common this condition is by taking small tissue samples (biopsies) from the wrist during surgery. If these samples show the amyloid protein, which can affect the heart, participants will undergo additional tests to check their heart health, including blood tests and a special scan.

To be eligible for this trial, participants need to be men over 65 years old or women over 75 years old who are scheduled for carpal tunnel surgery. They must also be able to give informed consent, meaning they understand and agree to participate in the study. If you join this trial, you can expect to have some extra tests done to check for heart issues if the initial biopsy shows amyloid. It's important to note that this study is specifically looking for patients who do not have known amyloidosis from other causes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Males above 65 years of age, females above 75 years of age.
• • Scheduled idiopathic carpal tunnel release surgery.
• • Informed written consent.
• Exclusion Criteria:
• • Operation by other indication, e.g.
• • Fracture
• • Ganglion
• • Known amyloidosis