Comparison H-FIRE and Laparoscopic RP in Treating Men With Localized Prostate Cancer
Launched by SHANGHAI EAST HOSPITAL · Feb 19, 2020
Trial Information
Current as of August 19, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different ways to treat men with localized prostate cancer: high-frequency irreversible electroporation (H-FIRE) and laparoscopic radical prostatectomy (Laparoscopic RP). The goal is to see which method works better in terms of patient health and cancer control. H-FIRE is a newer technique that uses electrical pulses to destroy cancer cells, while laparoscopic RP involves surgically removing the prostate using smaller incisions.
To participate, men must be under 80 years old, have a specific level of prostate-specific antigen (PSA) in their blood, and have a certain stage of cancer that hasn't spread. They should also understand the study and agree to take part by signing a consent form. Participants will not be eligible if they have had previous cancer treatments, certain recent surgeries, or other conditions that would make it unsafe for them to join. This trial is not yet recruiting participants, but it aims to provide valuable information on the best treatment options for prostate cancer in the future.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Age less than 80 years old.
- • 2. PSA\<20ng/ml.
- • 3. Clinical stage ≤T2c.
- • 4. Biopsy Gleason score ≤4+4.
- • 5. No evidence of metastasis.
- • 6. Fully understand the clinical trial protocol and sign the informed consent
- Exclusion Criteria:
- • 1. Any previous treatment to PCa.
- • 2. Any previous surgery within 3 months.
- • 3. Contraindications to MRI, bone scan, or PSMA-PET (eg, metal implant, contrast agent allergy).
- • 4. History of any other malignant tumour.
- • 5. Any other conditions that make the investigator judge that participants are not suitable for this trial.
About Shanghai East Hospital
Shanghai East Hospital, affiliated with Tongji University, is a leading healthcare institution in China dedicated to providing high-quality medical services, education, and research. Renowned for its advanced clinical practices and cutting-edge technologies, the hospital plays a pivotal role in the advancement of medical science through innovative research and clinical trials. Committed to improving patient outcomes, Shanghai East Hospital collaborates with various stakeholders to explore new therapies and treatment modalities, enhancing the collective understanding of health and disease. Their clinical trial initiatives focus on addressing pressing medical needs while ensuring the highest ethical standards and patient safety.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Shanghai, Shanghai, China
Patients applied
Trial Officials
Haifeng Wang, MD
Principal Investigator
Shanghai East Hospital,Tongji University School of Medicine
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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