Comparison Between Biopsied and Non-biopsied Intracytoplasmatic Sperm Injection (ICSI) Embryos and Natural Pregnancy Embryos

Launched by WAEL ELBANNA CLINIC · Feb 20, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the differences between embryos created through a process called Intracytoplasmic Sperm Injection (ICSI) that have been genetically tested (biopsied) and those that have not been tested (non-biopsied). It also compares these embryos to those conceived naturally. The goal is to find out if taking a small sample from the embryo affects its growth and development, and to see if there are any differences in health markers during pregnancy between these groups.

To participate in this study, women need to be pregnant with a single baby (singleton) and have confirmed their pregnancy through an ultrasound at around six weeks. Participants must be between 20 and 40 years old, non-smokers, and have a healthy body weight. Those who have certain medical conditions that affect pregnancy, like blood clotting disorders or uterine abnormalities, aren’t eligible. If you join this study, your medical records will be reviewed, and you'll undergo some blood tests and ultrasounds to monitor your health and the health of your baby. This research aims to provide more information on how genetic testing of embryos may impact pregnancy outcomes.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Singleton pregnant women
• • 2. Pregnancy confirmation by ultrasound at week 6 of gestation either by normal pregnancy or ICSI (Biopsied and Non-Biopsied)
• • 3. Between the age of 20 and 40 years.
• • 4. Non-smokers.
• • 5. BMI must be between 19 and 40
• Exclusion Criteria:
• • 1. Those with anti-phospholipid syndrome confirmed by serological tests
• • 2. Those with any hematological and immunological disorders
• • 3. Women with uterine abnormalities have not been corrected.
• • 4. Women with systemic diseases that cannot be controlled or managed