High Resolution Imaging for Analysis of MVNT

Launched by FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD · Feb 24, 2020

Keywords

ClinConnect Summary

This clinical trial is looking at a condition called MVNT, which stands for multinodular and vacuolating neuronal tumor of the cerebrum. This is a benign (non-cancerous) brain lesion that is not well understood and often presents in the temporal lobes of the brain. The trial aims to improve how these lesions are diagnosed using advanced MRI techniques, which could help prevent unnecessary surgeries for patients who actually do not need them.

To participate in this study, you must be over 18 years old and have had a first MRI that suggests you might have MVNT based on specific imaging criteria. This includes seeing a clustered appearance in the MRI images and certain signals that indicate the nature of the lesion. The study is currently recruiting participants of all genders. If you decide to join, you'll undergo more detailed MRI scans to help researchers understand how to better identify this condition. It’s important to note that individuals who cannot have an MRI or are pregnant are not eligible to participate. This study could lead to better diagnostic tools, ultimately improving care for patients with MVNT.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient over 18 years of age
• * Prospective inclusion of all patients with suspected MVNT on a first exploratory MRI: at least the 2 major criteria associated with at least 1 minor criterion will be required to fit into the definition of suspected MVNT:
• * Major criteria :
• • Multinomodular clustered appearance
• • Franc hypersignal FLAIR/T2
• * Minor criteria :
• • No mass effect
• • Hyposignal T1
• • Having received informed information about the study and having given express consent to participate in the study
• Exclusion Criteria:
• • Contraindication to MRI
• • Patient benefiting from a legal protection measure
• • Pregnant or breastfeeding woman
• Secondary exclusion criteria:
• • - No characterization MRI done