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Search / Trial NCT04288869

Change in Brain Perfusion During Induction of General Anesthesia

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Feb 26, 2020

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Cerebral Perfusion General Anesthesia Hypotension Transcranial Doppler Bispectral Index Near Infrared Spectroscopy

ClinConnect Summary

**Clinical Trial Summary: Change in Brain Perfusion During Induction of General Anesthesia**

This clinical trial is studying how the brain's blood flow changes during the start of general anesthesia, specifically when using certain medications. The researchers want to find out if low blood pressure during anesthesia affects blood flow to the brain, which could impact a patient's recovery and overall well-being. They will closely monitor brain blood flow and oxygen levels, as well as how well the brain is functioning, using special tools during procedures related to interventional radiology and orthopedic surgery. This information is important because it can help doctors understand how to manage blood pressure better during anesthesia and improve patient safety.

To be eligible for this study, participants need to be adults aged 18 or older who are scheduled for a procedure that requires general anesthesia. They should also agree to take part in the research. However, individuals under 18, pregnant women, or those who do not want to participate cannot join. Participants can expect to undergo a series of tests that measure blood flow and brain function, both during and after episodes of low blood pressure. Overall, this trial aims to gather valuable information that could lead to safer anesthesia practices and better outcomes for patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Major patients (≥ 18 years old)
  • Eligible for an interventional radiology procedure or orthopedic surgery under general anesthesia.
  • Patients who expressed their non-opposition to participation in this research
  • Exclusion Criteria:
  • Patients under the age of 18.
  • Patient opposed to participation in the protocol
  • Pregnant woman
  • Patient under judicial protection measure
  • Patient without affiliation to a social security scheme-

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Paris, , France

Patients applied

0 patients applied

Trial Officials

Joaquim MATEO, MD

Study Director

Assistance Publique - Hôpitaux de Paris

Fabrice VALLEE, MD

Principal Investigator

Assistance Publique - Hôpitaux de Paris

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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