Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

Launched by MEDICAL UNIVERSITY OF VIENNA · Feb 26, 2020

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to help extremely preterm infants breathe better while they are on a specific type of ventilation called High Frequency Oscillatory Ventilation (HFOV). The researchers want to see if a method that involves adjusting the lung settings based on oxygen levels can improve how well these infants are getting oxygen. The goal is to lower a measurement called the oxygen saturation index (OSI), which helps doctors understand how effectively the lungs are working.

To be eligible for this study, infants must be born before 28 weeks of pregnancy and not older than 29 weeks of postmenstrual age. They should be receiving HFOV for their breathing support. However, infants with certain heart, lung, or brain problems, or those with specific genetic conditions, cannot participate. If eligible, parents can expect their infants to be closely monitored during the trial, and their healthcare team will provide information and support throughout the process.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: Preterm infants
• • born below 28 weeks of gestational age
• • not older than 29 weeks of postmenstrual age
• • receive HFOV
• Exclusion Criteria:
• • known congenital anomalies of the heart, of the lung, and/or of the central nervous system
• • known chromosomal abnormalities
• • participation in other intervention trials