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Search / Trial NCT04291521

Prospective Study of Induction Medications Used in the Trauma RSI

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Feb 27, 2020

Trial Information

Current as of July 01, 2025

Not yet recruiting

Keywords

Trauma Induction Medications Rapid Sequence Intubations Outcomes

ClinConnect Summary

This clinical trial is designed to compare three different medications—propofol, etomidate, and ketamine—used to help patients with trauma during a procedure called intubation, which is when a tube is placed in the airway to help with breathing. The study aims to find out which of these medications works best for adult trauma patients who need intubation within 24 hours of being admitted to the hospital.

To participate in the trial, individuals must be at least 18 years old and have experienced trauma that requires intubation soon after being admitted to the emergency department or operating room. However, people who were intubated without these medications or who received different medications will not be eligible. If you join the trial, you can expect to receive one of the three medications as part of your treatment, and the outcomes will be closely monitored to help determine the best option for future patients in similar situations.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Trauma patients \>=18 yo requiring intubation within 24 hours of admission in either the ED or OR
  • Patients received propofol, etomidate, or ketamine for induction agent
  • Exclusion Criteria:
  • Patients who were intubated without induction agent medications
  • Patients intubated outside of the hospital or in the field
  • Patients who were intubated with an induction agent other than etomidate, ketamine, or propofol

About University Of Southern California

The University of Southern California (USC) is a prestigious research institution located in Los Angeles, California, known for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USC leverages its extensive resources, interdisciplinary expertise, and state-of-the-art facilities to conduct cutting-edge research aimed at improving patient outcomes and public health. The university fosters collaboration among its diverse faculty and students, ensuring a dynamic environment for the development and implementation of clinical studies that adhere to the highest ethical and scientific standards. Through its clinical trials, USC aims to contribute to the advancement of medical science and the translation of research findings into practical applications that benefit communities locally and globally.

Locations

Los Angeles, California, United States

Patients applied

0 patients applied

Trial Officials

Catherine M Kuza, MD

Principal Investigator

Keck School of Medicine of the University of Southern California

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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