SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction

Launched by KAROLINSKA INSTITUTET · Mar 2, 2020

Keywords

ClinConnect Summary

This clinical trial, called SEQUAR, is comparing two different types of grafts used in surgery to repair the Anterior Cruciate Ligament (ACL), which is a key ligament in the knee that can be injured during sports or physical activities. The two grafts being studied are taken from the semitendinosus muscle (located in the back of the thigh) and the quadriceps muscle (located in the front of the thigh). The goal is to see which graft works better for patients who need ACL reconstruction.

To be eligible for this trial, participants should be between the ages of 18 and 40 and have a Tegner score of 7 or higher before their injury, which indicates they were very active in sports. Certain individuals, like those who have had multiple knee injuries or previous knee surgeries, may not qualify. If you join the study, you’ll receive one of the two grafts during your ACL surgery, and your recovery will be closely monitored. This trial is taking place at the Capio Artro Clinic in Stockholm, where the doctors have a lot of experience with these types of surgeries. If you're considering participating, it could help improve ACL repair techniques for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pre-injury Tegner Activity Scale≥7
• • Intended return to sports to prior sport and Tegner Activity Scale Level
• • Time between injury and inclusion not more than 6 months
• • MR verified ACL rupture
• Exclusion Criteria:
• • Previous knee injury with symptoms before ACL injury
• • Neurological disease, inflammatory disease, connective tissue disease or balance disorder
• • Previous lower limb fracture or surgery
• • Laxity in the medial collateral ligament (MCL) and lateral collateral ligament (LCL) \> grade 1
• • PCL rupture or Multiligament knee injury (MLKI)
• • Radiographic sign of osteoarthritis (OA)
• • Previous knee surgery or ligament injury in contralateral knee
• • Beighton score ≥ 5