Defecation Function and Quality of Life in the Patients Treated With Surgery for Slow Transit Constipation

Launched by THIRD MILITARY MEDICAL UNIVERSITY · Mar 7, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how effective surgery is in improving bowel function and the quality of life for people who suffer from slow transit constipation (STC). STC is a condition where patients struggle to have regular bowel movements, often relying on laxatives or other treatments that may not work. The trial specifically looks at two types of surgery called total and subtotal colectomy to see how they help patients both in the short term and over a five-year period.

To participate in this trial, candidates must be between the ages of 65 and 74, have severe constipation symptoms that have not improved with other treatments for over a year, and show specific test results indicating poor bowel movement function. Participants will undergo surgery and then be monitored regularly to assess their bowel function and quality of life. This study aims to provide valuable insights into how surgery can help improve daily life for those with STC, making it an important option for patients seeking relief from their symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. The clinical manifestations all met the Roman IV standard for the diagnosis of functional constipation.
• • 2. Patients with severe constipation symptoms were unable to defecate naturally and need laxatives to assist defecation or still unable to defecate.
• • 3. Colonic transport tests showed that the opaque X-ray markers remained more than 20% after 72 hours.
• • 4. All conservative treatment for more than 1 year failed.
• • 5. Patients had a strong desire for surgery, and no other contraindications to surgery.
• Exclusion Criteria:
• • 1. Megacolon was detected with barium enema examination.
• • 2. Colonoscopy suggested the presence of intestinal organic lesions or a history of colorectal cancer treatment.
• • 3. Gastric and small intestinal transport dysfunction.
• • 4. There are depression, anxiety and other mental symptoms.
• • 5. Constipation type irritable bowel syndrome.
• • 6. History of inflammatory bowel disease.