Effect of Non-surgical Periodontal Treatment on Cardiovascular Risk Markers
Launched by MAHIDOL UNIVERSITY · Mar 10, 2020
Trial Information
Current as of August 21, 2025
Completed
Keywords
ClinConnect Summary
CHD patients or non-CHD with or without periodontitis were included. They were provided with non-surgical periodontal therapy (NSPT). Periodontal parameters and cardiovascular risk markers were measured at baseline and 3 months and 6 months after NSPT.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • non-CHD or CHD (at least 50% diameter stenosis in at least one coronary artery and clinically stable with absence of any potentially confounding inflammatory conditions for at least 6 months)
- • had at least 14 natural teeth excluding third molars
- Exclusion Criteria:
- • received anticoagulant drugs
- • had chronic conditions (e.g. diabetes mellitus, rheumatoid arthritis, malignancy, autoimmune disease) or acute conditions (e.g. trauma, surgery) or medications known to affect systemic inflammatory markers (e.g. antibiotics, immunosuppressive, contraceptives) within 3 months
- • pregnancy or lactation
- • presence or history of other infections
- • periodontal treatment within 6 months
- • tooth extractions within 2 months prior to the study.
About Mahidol University
Mahidol University, a premier institution in Thailand, is dedicated to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the university leverages its extensive expertise in medical and health sciences to facilitate rigorous scientific investigations aimed at improving patient care and public health outcomes. With a commitment to ethical practices and collaboration, Mahidol University fosters multidisciplinary approaches, engaging a diverse array of researchers and healthcare professionals to drive meaningful advancements in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ratchathewi, Bangkok, Thailand
Ratchathewi, Bangkok, Thailand
Ratchathewi, Bangkok, Thailand
Patients applied
Trial Officials
Supanee Rassameemasmaung, PhD
Principal Investigator
Mahidol University Faculty of Dentistry
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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