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Search / Trial NCT04305171

Effect of Non-surgical Periodontal Treatment on Cardiovascular Risk Markers

Launched by MAHIDOL UNIVERSITY · Mar 10, 2020

Trial Information

Current as of August 21, 2025

Completed

Keywords

Coronary Heart Disease, Peridontitis,

ClinConnect Summary

CHD patients or non-CHD with or without periodontitis were included. They were provided with non-surgical periodontal therapy (NSPT). Periodontal parameters and cardiovascular risk markers were measured at baseline and 3 months and 6 months after NSPT.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • non-CHD or CHD (at least 50% diameter stenosis in at least one coronary artery and clinically stable with absence of any potentially confounding inflammatory conditions for at least 6 months)
  • had at least 14 natural teeth excluding third molars
  • Exclusion Criteria:
  • received anticoagulant drugs
  • had chronic conditions (e.g. diabetes mellitus, rheumatoid arthritis, malignancy, autoimmune disease) or acute conditions (e.g. trauma, surgery) or medications known to affect systemic inflammatory markers (e.g. antibiotics, immunosuppressive, contraceptives) within 3 months
  • pregnancy or lactation
  • presence or history of other infections
  • periodontal treatment within 6 months
  • tooth extractions within 2 months prior to the study.

About Mahidol University

Mahidol University, a premier institution in Thailand, is dedicated to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the university leverages its extensive expertise in medical and health sciences to facilitate rigorous scientific investigations aimed at improving patient care and public health outcomes. With a commitment to ethical practices and collaboration, Mahidol University fosters multidisciplinary approaches, engaging a diverse array of researchers and healthcare professionals to drive meaningful advancements in clinical research.

Locations

Ratchathewi, Bangkok, Thailand

Ratchathewi, Bangkok, Thailand

Ratchathewi, Bangkok, Thailand

Patients applied

0 patients applied

Trial Officials

Supanee Rassameemasmaung, PhD

Principal Investigator

Mahidol University Faculty of Dentistry

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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