Management of Prelabor Rupture of the Membranes at Term

Launched by RAMBAM HEALTH CARE CAMPUS · Mar 11, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how to manage a situation called prelabor rupture of membranes (when the water breaks before labor starts) in pregnant women. The researchers want to find out if starting labor early with a medication called oxytocin is better than simply waiting for labor to begin naturally within 24 hours. They are focusing on the risks of infections that can happen when the membranes have been ruptured for a long time.

To participate in this trial, women must be first-time mothers (primiparous) who are at least 37 weeks pregnant with a single baby in the head-down position. Unfortunately, women under 19, those with multiple pregnancies, or those experiencing other complications (like active labor or infections) cannot take part. If eligible, participants can expect to receive either the early intervention with oxytocin or the usual care while being closely monitored for their health and the health of their baby. This trial is currently recruiting participants, and it aims to improve the care provided to mothers and their babies during this critical time.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Primiparous women with a singleton pregnancy that are admitted with prelabor rupture of membranes.
• • 2. Women at gestational age 370/7 or more.
• • 3. Vertex presentation.
• Exclusion Criteria:
• • 1. Age 18 and under.
• • 2. High order gestation.
• • 3. Women with contraindication for a vaginal delivery.
• • 4. Active labor.
• • 5. Documented fetal anomalies.
• • 6. Known or suspected intrauterine infection (temperature \> 38 degrees, leucocytosis).
• • 7. Non reassuring fetal heart rate tracing.
• • 8. Positive group B streptococcus status.