Transcranial Direct Current to Treat Epilepsy at Home

Launched by STANFORD UNIVERSITY · Mar 13, 2020

Keywords

ClinConnect Summary

Electrical stimulation is a promising new therapy to reduce seizures, but current methods require inserting wires under the skull or into brain. This project will use direct-current electrical stimulation pulses delivered from scalp electrodes to provide stimulation. The goal is to reduce seizures without the need for surgery.

2. PROCEDURES:

2.1. Baseline: Upon signing of consent, subjects will have an initial screening clinic visit with a neurological history and examination. You will record a seizure diary for one month prior to start of stimulation.

2.2. Baseline EEGs: A 2-hour record...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-100, inclusive.
• • Has a clinical diagnosis of epilepsy
• • Has at least 4 countable seizures per month
• • Has not had control with at least 2 anti-seizure medicines
• • Able to maintain a constant medication for duration of the study (rescue meds allowed)
• • Subject or legally authorized representative is able to understand consent and keep a seizure diary in English
• Exclusion Criteria:
• • A disease likely to progress over course of the study
• • Psychogenic non-epileptic seizures
• • Suicide attempt or psychiatric hospitalization past 2 years
• • A skin condition interfering with scalp electrodes or allergy to silver
• • Women will verify not pregnant, and if applicable, have a serum pregnancy test