Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study
Launched by UNIVERSITY HOSPITAL HRADEC KRALOVE · Mar 15, 2020
Trial Information
Current as of July 21, 2025
Unknown status
Keywords
ClinConnect Summary
SAH group - in patients with SAH and documented vasospasms by digital subtraction angiography (DSA) of trans-cranial doppler imaging (TCD) of arteria cerebri media nimodipine is indicated because it is proven to improve the clinical outcome. The disfunction of cerebral microcirculation in rats with SAH has been documented \[1-6\]. Changes in sublingual microcirculation in patients with SAH with documented vasospasms with nimodipine has not been described.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • adulthood
- • ICU admission
- • diagnosis of non-traumatic subarachnoid hemorrhage
- Exclusion Criteria:
- • inherited coagulation disorder
- • rheumatic disease
- • microangiopathy
- • patient of representative refusal
About University Hospital Hradec Kralove
University Hospital Hradec Králové is a leading academic medical center in the Czech Republic, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge medical practices with rigorous scientific inquiry, fostering collaborations that enhance patient care and treatment outcomes. With a multidisciplinary team of experts, state-of-the-art facilities, and a strong emphasis on ethical standards and patient safety, University Hospital Hradec Králové plays a pivotal role in translating research findings into practical applications that benefit the broader medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hradec Králové, Třebeš, Czechia
Hradec Králové, , Czechia
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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