Tranexamic Acid Infusion During Elective Spine Surgery

Launched by ALBANY MEDICAL COLLEGE · Mar 16, 2020

Keywords

ClinConnect Summary

This will be a prospective randomized control, double-blinded investigation. The Investigators will recruit patients undergoing elective, primary, decompressive lumbar surgery via a posterior surgical approach of less than 3 levels. This includes patients undergoing decompressive lumbar laminectomies with or without fusion. Fusion may include posterior interbody and/or posterior lateral techniques with instrumentation.

There will be 3 treatment arms with the goal of 65 patients in each arm. Patients will be randomized pre-operatively and enrolled into the IV transexamic acid group (receivi...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing decompressive lumbar laminectomy with or without fusion
• • Primary surgical procedure
• • Competent adult able to give informed consent
• • Age \>18
• Exclusion Criteria:
• • h/o DVT or PE
• • h/o seizure
• • h/o coagulopathy
• • Diagnosis of malignancy or infection as indication for surgical decompression
• • Abnormal pre-operative PT/INR, aPTT, bleeding time
• • Platelet count \< 100
• • Patients requiring therapeutic heparin or lovenox bridges prior to and/or after surgery
• • Allergy to TXA
• • Pregnant women and prisoners
• • Renal insufficiency