Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

Launched by SOUTHWEST AUTISM RESEARCH & RESOURCE CENTER · Mar 24, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how certain biological markers in the body relate to neurological and developmental disorders like Autism Spectrum Disorder (ASD), epilepsy, brain tumors, and other related conditions. Researchers hope to understand the connections between metabolism (how our body uses food for energy) and our immune system in these disorders. If you or your child is between the ages of 0 and 17 and has been diagnosed with ASD or other specified conditions, you may be eligible to participate.

Participants can expect to visit the study site up to five times for simple procedures, including a blood draw (when you give a small sample of blood), behavioral assessments, and questionnaires about health and behavior. There is no cost for any of the visits or tests related to this study. It’s important to note that participants cannot have had serious reactions to blood draws in the past, and females who are pregnant or planning to become pregnant cannot participate. This study is currently looking for participants, and your involvement could help improve understanding of these conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria (ASD):
• • 1. ASD, as defined by either a gold standard measure for ASD diagnosis, the Autism Diagnostic Observation Schedule (ADOS); the Autism Diagnostic Interview-Revised (ADI-R); and/or a comprehensive assessment that is consistent with ASD, in the opinion of the principal investigator. For those the PI believes a prospective diagnosis of ASD is warranted, a formal diagnostic assessment will be scheduled at screening.
• • 2. 0 years through 17 years 11 months of age
• • Inclusion Criteria (TD, MD, Epilepsy, Brain Tumor, Psychiatric)
• • 1. 0 years to 17 years 11 months of age
• Exclusion Criteria (All):
• • 1. History of a significant adverse reaction to a prior blood draw
• • 2. In females of reproductive age, pregnancy or plans to become pregnant
• • 3. Any other historical event/information that may, in the opinion of the PI, be a reason to exclude the child from participation.