Intraoperative Navigation for Surgically Precise Resection of the Chest (INSPIRE)

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Mar 30, 2020

Keywords

ClinConnect Summary

The INSPIRE trial is studying a new way to help surgeons remove chest wall lesions more accurately during surgery. This is important because making sure the surgeon removes enough tissue around the lesion, known as the surgical margin, can help prevent complications like needing more surgery or complex repairs afterward. The trial uses advanced technology that combines patient images with real-time information during the operation, aiming to improve the precision of the surgery.

To participate in the trial, you need to be at least 18 years old, able to provide informed consent (which means you understand the study and agree to take part), and scheduled for surgery to remove a chest wall lesion. However, if you have certain medical conditions, like unresectable lesions or specific metal implants that could interfere with the technology, you may not be eligible. If you join the trial, you can expect to receive careful monitoring and support throughout the process, and you'll be contributing to important research that could improve surgical outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Ability to provide informed consent
• • 2. Scheduled to undergo surgical resection of a chest wall lesion
• • 3. At least 18 years of age
• • 4. Must sign and be given a copy of the written informed consent form
• Exclusion Criteria:
• • 1. Unresectable lesions or unstable patient condition, for which surgery is not recommended
• • 2. Participants with metallic implantation, such as ribs fixations, a pacemaker, or pedicle screws, which may affect the accuracy of CBCT
• • 3. Excluded at the discretion of the clinical investigator/surgeon, if they are enrolled in other studies that will result in combined radiation exposure exceeding standard of care
• • 4. Pregnant, lactating, or planning to become pregnant during the period of the evaluation