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Search / Trial NCT04331392

Online Memory Intervention for Individuals with Traumatic Brain Injury

Launched by TORONTO REHABILITATION INSTITUTE · Mar 31, 2020

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Environmental Enrichment Spatial Navigation Traumatic Brain Injury Neurorehabilitation Telerehabilitation Hippocampus

ClinConnect Summary

This clinical trial is studying a new online program designed to help improve memory and brain health in people who have experienced moderate to severe traumatic brain injuries (TBI). The program focuses on spatial navigation, which is how we understand and move through spaces around us. Researchers want to see if this online intervention can be effective and easy for people to use.

To participate in this trial, you must be between 18 and 55 years old, have been diagnosed with a moderate to severe TBI, and have experienced memory issues for at least 24 hours. You should also live in the Greater Toronto Area, know how to use basic computer skills, and be able to use at least one arm to operate a computer. Unfortunately, if you have certain other neurological disorders, developmental disorders, or specific health conditions, you may not be eligible. If you join the study, you can expect to engage with the online program and contribute to research that could lead to better treatment options for others with similar injuries.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • acute care diagnosis of m-sTBI
  • PTA of 24 hours or more and/or lowest GCS \<13
  • positive CT or MRI; (4) between 18 to 55 years of age
  • fluency in English; (6) competency to provide informed consent or availability of a legal decision maker
  • basic computer skills (use of internet/email, mouse and arrow keys)
  • functional use of at least one upper extremity for computer use
  • resident of Greater Toronto Area (to facilitate access to the MRI).
  • Exclusion Criteria:
  • neurological disorder other than TBI (e.g., dementia, stroke)
  • diagnosis of a neurodevelopmental disorder
  • TBI sustained before age 18
  • systemic comorbidities (e.g., lupus, diabetes)
  • current diagnosis of aphasia
  • presence of metal inside the body (e.g., surgical clips, pacemaker) leading to ineligibility for an MRI.

About Toronto Rehabilitation Institute

The Toronto Rehabilitation Institute (TRI) is a leading research and clinical care organization dedicated to advancing rehabilitation science and enhancing the quality of life for individuals with disabilities and chronic health conditions. As a prominent sponsor of clinical trials, TRI focuses on innovative approaches to rehabilitation, integrating cutting-edge research with practical applications in patient care. The institute collaborates with interdisciplinary teams of experts to explore new therapies and technologies, ensuring that findings translate into effective treatments. With a commitment to improving patient outcomes, TRI is at the forefront of rehabilitation research, striving to empower individuals on their journey to recovery.

Locations

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Robin E Green, PhD; CPsych

Principal Investigator

Toronto Rehabilitation Institute

Asaf Gilboa, PhD

Principal Investigator

Baycrest Health Sciences

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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