The Genomic Medicine at VA Study

Launched by BOSTON VA RESEARCH INSTITUTE, INC. · Mar 31, 2020

Keywords

ClinConnect Summary

The Genomic Medicine at VA Study is looking at how well a special genetic test, called a polygenic risk score, can predict the likelihood of developing certain diseases. This study focuses on patients who may be at higher genetic risk for conditions like coronary artery disease, atrial fibrillation (an irregular heartbeat), type 2 diabetes, colorectal cancer, breast cancer, and prostate cancer. Over a period of 24 months, researchers will track how quickly these diseases are diagnosed in participants.

To be eligible for this study, you should be between 50 and 70 years old and not have been diagnosed with any of the six diseases being studied. The study is currently recruiting participants of all genders who meet these criteria. If you join, you can expect to undergo testing and regular check-ins over the two years to monitor your health. This research aims to provide more personalized medicine based on your genetic risk, which could help in early detection and prevention of these serious diseases.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 50-70 years at enrollment
• • No known diagnosis of the following conditions, initially screened by the International Classification of Disease (ICD) codes or other electronic health record (EHR) data using validated methods and then confirmed with potential patient-participants during recruitment: coronary artery disease, atrial fibrillation, type 2 diabetes, colorectal cancer, breast cancer, prostate cancer
• Exclusion Criteria:
• * Patients will be ineligible if they:
• • Have a known diagnosis of at least one of the six diseases of interest
• • Are younger than age 50 or older than age 70
• • Are pregnant
• • Are incarcerated or institutionalized