Continuous Versus Intermittent cARdiac Electrical moNitorinG

Launched by WASHINGTON UNIVERSITY SCHOOL OF MEDICINE · Apr 2, 2020

Keywords

ClinConnect Summary

This clinical trial is studying a new way to monitor the heart in patients who are taking certain medications that can cause heart problems, specifically a condition called Torsades de Pointe and Long QT Syndrome. The researchers want to see if a continuous patch monitoring system, which sticks to the skin and tracks heart activity, is better than the standard method of using electrocardiograms (ECGs) that usually requires a visit to a doctor's office.

To participate in this study, you need to be at least 18 years old and diagnosed with specific types of cancer, such as acute promyelocytic leukemia or certain solid tumors, while starting treatment with certain medications. It's also important that you do not have an allergy to adhesive patches. If you join the study, you can expect to wear the monitoring patch for a period, and the researchers will check your heart's rhythm to gather important information. Keep in mind that the study is currently recruiting participants, and your involvement could help improve heart monitoring for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of acute promyelocytic leukemia (APL) and being initiated on standard of care arsenic trioxide OR Diagnosis of solid tumor and being initiated on standard of care capecitabine (alone or as part of combination treatment) OR Diagnosis of solid tumor and being initiated on standard of care ribociclib (alone or as part of combination treatment)
• • At least 18 years of age.
• • No allergy to adhesive patches.
• • Able to understand and willing to sign an IRB-approved written informed consent document.
• Exclusion Criteria:
• • Younger than 18 years of age
• • Allergy to adhesive patches