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Search / Trial NCT04342234

Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden.

Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · Apr 8, 2020

Trial Information

Current as of July 25, 2025

Recruiting

Keywords

Cleft Lip Neural Network Palatal Plate Therapy Palatal 3 D Geometry Palatal Shape Reconstruction

ClinConnect Summary

This clinical trial is focused on developing a new technology using a computer program called a neural network to help better understand the shape of the palate (the roof of the mouth) in infants with cleft lip and palate. By analyzing routine photographs and models of the palate taken from patients at the University Hospital Basel, researchers hope to create a system that can accurately compute the three-dimensional shape of the palate from just a single photo. This innovation aims to make treatment for cleft lip and palate easier and more effective.

To participate in this study, patients need to have a cleft lip and palate condition and must have certain types of models and images taken of their palate over the years (from 1970 to 2025). The study is open to all genders and is currently recruiting participants. If eligible, patients can expect to contribute to research that could improve treatment for future patients with similar conditions. Additionally, it's important to note that individuals with documented rejections of previous treatments will not be included in the trial.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with cleft lip and palate malformation with available routinely performed plaster cast model from palatal impressions, intraoral scans from the palate and corresponding images of the cleft palate (1970 till 2025)
  • Exclusion Criteria:
  • Existence of a documented rejection

About University Hospital, Basel, Switzerland

The University Hospital Basel, Switzerland, is a leading academic medical center renowned for its commitment to cutting-edge research and innovative patient care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise and state-of-the-art facilities to advance medical knowledge and therapeutic options across various disciplines. With a collaborative approach that integrates clinical practice and scientific inquiry, the University Hospital Basel fosters an environment conducive to rigorous clinical trials, ensuring the highest standards of safety and efficacy. Its strategic focus on patient-centered research aims to translate scientific discoveries into tangible health solutions, benefiting both local and global communities.

Locations

Basel, , Switzerland

Patients applied

0 patients applied

Trial Officials

Andreas Müller, PD Dr. med. Dr. med. dent. Dr.

Principal Investigator

Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Basel

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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