Small Doses Muscle Relaxant in General Anesthesia

Launched by MANSOURA UNIVERSITY · Apr 10, 2020

Keywords

ClinConnect Summary

This clinical trial is investigating the effects of very small doses of a muscle relaxant used during general anesthesia on how well patients breathe after surgery. The main goal is to measure how quickly patients can be taken off a breathing tube after surgery, which indicates how quickly their muscle strength returns. Researchers will also look at how satisfied the surgeons are with the surgical conditions, whether there are any breathing issues after the surgery, and how well the lungs are functioning using simple tests and ultrasound.

To participate in this study, adults between the ages of 20 and 50 who are scheduled for certain types of non-heart or lung surgeries may be eligible. Participants will need to give their consent and will be monitored closely for 28 days after the surgery to check for any breathing complications. It's important to note that individuals with certain health conditions, like severe lung or kidney issues, or those taking specific medications, may not qualify. Overall, this study aims to improve patient recovery after surgery by understanding how low doses of muscle relaxants can affect breathing.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • adult patients
• • aged from 20 to 50 years old
• • scheduled for non-cardiothoracic surgery
• • under general anesthesia
• • in supine position
• • after informed consent
• Exclusion Criteria:
• • American Society of Anesthesiologists (ASA) score more than 3
• • suspected full stomach or who will undergo intervention expected to necessitate profound muscle relaxation or dressing interferes with ultrasound (US) probe positioning
• • Lung parenchymatous disease
• • renal disease
• • hepatic disease
• • neuromuscular disease
• • electrolytes imbalanc
• • on medication interfere with muscle contraction
• • with known allergy to any drug used in the study