Effect of Krill Oil on Cognitive Function in Adults

Launched by PUSAN NATIONAL UNIVERSITY YANGSAN HOSPITAL · Apr 12, 2020

Keywords

ClinConnect Summary

Previous animal studies have indicated that Krill oil may have the ability to improve cognitive function. Therefore, the investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Krill oil on cognitive function in adults with subjective memory impairment for 12 weeks; the safety of the compound are also evaluate. The Investigators examine chemical and metabolic parameters, and cognitive function at baseline, as well as after 6 and 12 weeks of intervention. One hundred adults were administered either 500 mg of Krill oil or a placebo each day for...

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Eligibility criteria

• Inclusion Criteria:
• • Global Deterioration Scale (GDS) 2 or 3
• Exclusion Criteria:
• • Abnormal liver or renal function (i.e., serum aminotransferase activity \> 3 times of upper limit of reference range and serum creatinine concentrations \> 1.2 mg/dL)
• • Diabetes (diagnosed clinically or fasting glucose level \> 126 mg/dL)
• • History of viral hepatitis or cancer
• • Uncontrolled hypertension
• • History of serious cardiac disease such as angina or myocardial infarction
• • History of gastrectomy
• • History of medication for psychiatric disease
• • Administration of oriental medicine including herbs within the past 4 weeks