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The MR-Linac Technical Feasibility Protocol

Launched by THE NETHERLANDS CANCER INSTITUTE · Apr 15, 2020

Trial Information

Current as of July 04, 2025

Recruiting

Keywords

Radiotherapy Mr Linac

ClinConnect Summary

The MR-Linac Technical Feasibility Protocol is a clinical trial looking at a new way to deliver radiation therapy for tumors. This study is exploring the use of Magnetic Resonance Imaging (MRI) combined with a linear accelerator, which is the machine that delivers radiation. By using MRI, doctors can get a clearer picture of the tumor and surrounding organs, helping them to adjust treatment in real-time. This could lead to more precise targeting of the tumor while reducing exposure to nearby healthy tissues, which can help lessen side effects.

To participate in this trial, you need to be at least 18 years old and scheduled to receive radiation therapy using the MR-Linac system. You should be in generally good health and able to understand and sign an informed consent form. However, if you are pregnant, have certain medical conditions, or experience claustrophobia, you may not be eligible. If you join the study, you can expect to undergo radiation therapy with advanced imaging techniques that aim to improve treatment outcomes while minimizing risks.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient, age ≥ 18 years, treated with radiation therapy on the MRL.
  • WHO performance 0-2.
  • Ability to understand and the willingness to sign a written informed consent document
  • Exclusion Criteria:
  • Contra-indications for an MRI examination.
  • Patient is pregnant.
  • Claustrophobia.
  • Patients \>140 kg and/or a body width \> 60 cm.
  • Patients with any other clinically significant medical condition which, in the opinion of the treating physician, makes it undesirable for the patient to participate in the study or which could jeopardize compliance with study requirements or severe psychiatric illness/social situation.

About The Netherlands Cancer Institute

The Netherlands Cancer Institute (NKI) is a leading research and treatment center dedicated to advancing the understanding and management of cancer. Renowned for its cutting-edge research, NKI fosters innovation in oncology through a multidisciplinary approach that integrates laboratory research, clinical trials, and patient care. With a commitment to translating scientific discoveries into effective therapies, the institute collaborates with national and international partners to enhance cancer treatment outcomes. NKI's state-of-the-art facilities and expertise in various cancer types position it as a pivotal contributor to the global fight against cancer, aiming to improve survival rates and quality of life for patients.

Locations

Amsterdam, , Netherlands

Patients applied

0 patients applied

Trial Officials

Marlies Nowee, MD, PhD

Principal Investigator

The Netherlands Cancer Institute

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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