Treatment of Resistant Depression by Repetitive Transcranial Magnetic Stimulation (rTMS) Multicentric Naturalistic Study

Launched by CENTRE HOSPITALIER DE VILLE-EVRARD, FRANCE · Apr 17, 2020

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called repetitive Transcranial Magnetic Stimulation (rTMS) for people with depression that has not improved with standard medications. rTMS is a non-invasive procedure that uses magnetic fields to stimulate specific areas of the brain. The trial aims to see how effective this treatment is for individuals who have tried at least two different antidepressants without success. Eligible participants must be between 65 and 74 years old, fluent in French, and agree to take part in the study by signing an informed consent form.

If you or a loved one join this study, you can expect to receive rTMS treatment and be monitored for its effects on your depression. It's important to know that certain individuals cannot participate, such as those with specific medical conditions like epilepsy or those who are pregnant. This trial aims to explore a promising new option for people struggling with resistant depression, potentially offering hope for better mental health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Presenting a depressive episode characterized as resistant according to the DSM 5 criteria
• • resistance is characterized by: non-response to at least two different antidepressants prescribed at effective doses for a duration greater than or equal to 6 weeks.
• • Patient who agrees to participate in the study and who has signed an informed consent.
• • Patient fluent in French
• • Affiliation to a social security scheme.
• • Women of childbearing age must be on contraception
• Exclusion Criteria:
• • Presenting a contraindication to TMS: intrafemale foreign body cranial, unstable epilepsy, cochlear implant, pacemaker, pregnancy
• • Presence of a psychotic disorder
• • Presence of an unstable medical condition
• • Presence of schizophrenia or persistent delusional disorder
• • Persons under guardianship, curatorship and safeguarding of justice.
• • Pregnant women,
• • Woman of childbearing age without effective contraception
• • Breastfeeding woman