Cognitive Impairment in Ageing People

Launched by YAMEI TANG · Apr 21, 2020

Keywords

ClinConnect Summary

This clinical trial is focused on understanding mild cognitive impairment (MCI) and neurocognitive disorders like Alzheimer's disease and vascular dementia in older adults. The goal is to learn more about how these conditions develop, how to identify them early, and how to treat them effectively. Researchers plan to create a comprehensive database that includes health information, brain scans, and blood samples from participants. This will help them track how many people with MCI go on to develop dementia and what factors might increase that risk.

To join the study, participants need to be over 50 years old and have a specific level of cognitive impairment that does not yet meet the criteria for dementia. They must be willing to give informed consent and undergo some tests, including blood samples and brain imaging. The study is currently recruiting participants and aims to help improve early detection and treatment of cognitive disorders, ultimately reducing the impact of these conditions on individuals and society.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients over 50 years old.
• • 2. Sign informed consent.
• • 3. According to DSM-IV, the diagnostic standard of dementia was not met.
• • 4. The clinical dementia rating (CDR) was 0.5.
• Exclusion criteria:
• • 1. Subjects with mental retardation.
• • 2. Refuse to have blood sampling, imaging and other examinations.
• • 3. Uncooperative subjects that have serious organic diseases, or have a history of mental illness, or have physical disability (including severe aphasia).
• • 4. Contraindications of MR scanning.
• • 5. Suffering from serious physical or mental illness.