Gracie Diet for Gastroesophageal Reflux Disease

Launched by JOHNS HOPKINS UNIVERSITY · Apr 23, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the Gracie Diet as a potential way to help people with gastroesophageal reflux disease (GERD), which is a common condition that causes symptoms like heartburn and regurgitation. The trial aims to see if following this specific diet can improve symptoms for patients who are still experiencing issues even while taking standard medications like proton pump inhibitors (PPIs) or H2 blockers. The Gracie Diet focuses on how to combine foods in a way that promotes better digestion and overall health, while also encouraging healthier eating habits.

To participate in this trial, individuals must be 18 years or older and currently experiencing GERD symptoms despite using certain medications for treatment. Participants will need to follow the Gracie Diet guidelines, which include avoiding specific food combinations and making healthier lifestyle choices, such as eating more fruits and vegetables. The trial is currently recruiting participants, and those who join can expect to learn more about managing their condition through dietary changes while contributing to valuable research that could help others with GERD in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18 years or older at registration.
• • Patients with ongoing symptoms of GERD: heartburn (pyrosis) mid-sternal chest pain, regurgitation of fluid or food, development of esophageal inflammation that may lead to swallowing dysfunction, or extraesophageal manifestations (i.e. cough, bronchospasms, and hoarseness).
• • Use of one of the following PPI medications: omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole or dexlansoprazole. And/or use of one of the following H2 blockers medications as well: famotidine, cimetidine, ranitidine or nizatidine.
• • Willing to comply with the Gracie diet regimen
• Exclusion Criteria:
• • Age \< than 18 years.
• • Patients unable to speak English.
• • Pregnancy or nursing.
• • Complicated oropharyngeal dysphagia or other condition with risk for aspiration from oral ingestion.
• • Exclusion of other causes of symptoms as mechanical gastrointestinal obstruction, Barrett's esophagus and cancer of the esophagus by standard radiographic or endoscopic test evidenced in the medical record chart.
• • A prior surgery of the upper gastrointestinal tract.
• • Failure to give informed consent.
• • Any other condition, which in the opinion of the investigator would impede compliance or hinder the completion of the study.