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Search / Trial NCT04363983

Interaction Between Host, Microenvironment and Immunity on Gastrointestinal Neoplasms

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Apr 24, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Gastrointestinal Cancer Micro Environment Immunity Host Microbiota

ClinConnect Summary

This clinical trial is exploring how the environment around tumors and the body's immune response affect the survival of patients with certain types of digestive cancers, such as colorectal, pancreatic, and stomach cancers. The goal is to understand the relationship between these factors and overall patient survival, which may help improve future treatments for these conditions.

To participate in the trial, patients must be at least 18 years old and have been diagnosed with specific digestive cancers between 1998 and 2030. They also need to be part of the French social security system. The trial is currently looking for volunteers, and interested individuals can expect to provide consent and possibly share information about their health to help researchers gather important data. It's important to note that pregnant or breastfeeding women, as well as those who may have difficulties following the study's guidelines, are not eligible to participate.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Carcinoma of colorectal, pancreatic, biliary tract or gastro-oesophageal, or neuroendocrine digestive tumors with cytologically or histologically proven, regardless of the stage;
  • Diagnosis between 1998 and 2030;
  • Be \>/= 18 years;
  • Have obtained signed informed consent (exemption for dead patients);
  • Affiliated to the French social security - welfare system in France (CMU included).
  • Exclusion Criteria:
  • Patient under tutoraship or curatorship;
  • Foreign patient under AME schema, a medical help from the state in France;
  • Pregnant or breastfeeding women (for prospective study);
  • Any clinical, psychological or social reason which should influence patient compliance with protocol, according to investigator;
  • Patient refusal.

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Boulogne Billancourt, , France

Patients applied

0 patients applied

Trial Officials

Frédérique PESCHAUD, MD, PhD

Principal Investigator

Digestive Surgery Department, Ambroise Paré Hospital, APHP

Cindy NEUZILLET, MD

Study Director

Digestive Surgery Department, Ambroise Paré Hospital, APHP

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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