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Search / Trial NCT04381663

CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes

Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · May 5, 2020

Trial Information

Current as of July 23, 2025

Enrolling by invitation

Keywords

Cervical Spinal Stenosis Cervical Myelopathy

ClinConnect Summary

Study A is a single centre cross-sectional study with two study groups, one that will be treated conservatively (stenosis) and one that will be treated surgically (stenosis and myelopathy).

Study B is a single centre longitudinal study where the same patient groups will be followed up during the course of their treatment.

Clinical, radiological, biomechanical (kinematic and electromyographic), neurological and neurophysiological data will be collected. Differences in and the relationship between the clinical, radiological, biomechanical, neurological and neurophysiological data will be de...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \> 18 years
  • Diagnosis of degenerative cervical spine stenosis defined by MRI (stenosis grade 2 or grade 3
  • Local clinical symptoms due to degenerative changes of the cervical vertebral column with or without clinically defined myelopathy
  • Exclusion Criteria:
  • Stenosis after trauma or neoplasm
  • Prior decompressive surgery
  • Previous spine or extremity surgery with a consequent sensorimotor impairment
  • Other pathologies than cervical spine stenosis causing gait disturbance
  • BMI \> 35 kg/m2
  • Use of walking aids
  • Inability to provide informed consent
  • Contraindications for recording of Motor evoked potentials (MEP)
  • Contraindications to safely undergo MRI

About University Hospital, Basel, Switzerland

The University Hospital Basel, Switzerland, is a leading academic medical center renowned for its commitment to cutting-edge research and innovative patient care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise and state-of-the-art facilities to advance medical knowledge and therapeutic options across various disciplines. With a collaborative approach that integrates clinical practice and scientific inquiry, the University Hospital Basel fosters an environment conducive to rigorous clinical trials, ensuring the highest standards of safety and efficacy. Its strategic focus on patient-centered research aims to translate scientific discoveries into tangible health solutions, benefiting both local and global communities.

Locations

Basel, , Switzerland

Patients applied

0 patients applied

Trial Officials

Annegret Mündermann, Prof. Dr.

Principal Investigator

University Hospital, Basel, Switzerland

Cordula Netzer, Dr. med.

Principal Investigator

University Hospital, Basel, Switzerland

Regina Schläger, PD Dr. med.

Principal Investigator

University Hospital, Basel, Switzerland

Martin Hardmeier, PD Dr. med.

Principal Investigator

University Hospital, Basel, Switzerland

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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