COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected with SARS-CoV-2: Multicentric Non Interventional Study

Launched by HOSPICES CIVILS DE LYON · May 15, 2020

Keywords

ClinConnect Summary

This clinical trial aims to study how the immune system responds in adult patients with COVID-19 who are hospitalized in the intensive care unit (ICU). Researchers want to understand how the immune response changes over time and how it relates to serious complications like organ failure or secondary infections in these patients. This information could help develop new treatments and identify ways to better manage patients in the ICU with COVID-19.

To participate in this study, individuals must be at least 18 years old, currently hospitalized in the ICU due to COVID-19, and have tested positive for the virus. Participants will have blood samples taken within the first day of their ICU stay. The goal is to gather important data that could improve future care for COVID-19 patients. It's important to note that this study does not involve any new treatments; it's focused solely on gathering information to better understand the disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Man or woman aged 18 or over,
• • 2. Hospitalization in intensive care for Sars-Cov-2 pneumopathy,
• • 3. First hospitalization in intensive care unit,
• • 4. Positive diagnosis of SARS-CoV2 infection carried out by PCR or by another approved method in at least one respiratory sample,
• • 5. Sampling in the first 24 hours after admission to intensive care unit (D0 / D1) feasible,
• • 6. Patient or next of kin who has been informed of the terms of the study and has not objected to participating.
• Exclusion Criteria:
• • 1. Pregnant or lactating woman,
• • 2. Person placed under legal protection,