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Search / Trial NCT04395248

Optimal Anesthesia for Morbidly Obese Patients

Launched by TAIPEI MEDICAL UNIVERSITY SHUANG HO HOSPITAL · May 14, 2020

Trial Information

Current as of July 21, 2025

Completed

Keywords

Obesity Anesthesia Enhanced Recovery After Surgery Difficult Intubation Preoxygenation Depth Of Anesthesia High Flow Nasal Cannula

ClinConnect Summary

The investigators will conduct a clinical trial using permuted block randomization and conforming to the CONSORT Statement to investigate multiple clinical outcomes in obese patients undergoing LSG at Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. Three randomizations will be conducted, including radial artery catheterization using ultrasound guidance or blind palpitation, preoxygenation using HFNC or CPAP, and volatile anesthesia with desflurane or sevoflurane with or without M-Entropy guidance. A computer-generated list of randomizations (Research Randomizer, www....

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 20 to 65 years
  • BMI ≥ 30 kg/m2
  • Undergoing laparoscopic sleeve gastrectomy at Shuang-Ho Hospital, Taiwan
  • Exclusion Criteria:
  • Severe cardiopulmonary disease
  • Psychiatric disorder
  • History of head and neck surgery or radiation therapy
  • Cervical spine injury
  • Renal insufficiency (estimated creatinine clearance \< 60 ml/min)
  • SpO2 \< 90% in room air
  • Hemodynamic instability
  • Preexisting arterial catheterization during the same visit within 7 days
  • Patient refusal

About Taipei Medical University Shuang Ho Hospital

Taipei Medical University Shuang Ho Hospital is a leading healthcare institution in Taiwan dedicated to advancing medical research and clinical care. As an integral part of Taipei Medical University, the hospital emphasizes innovation and excellence in patient treatment while fostering a collaborative environment for clinical trials. With a strong focus on multidisciplinary approaches and cutting-edge technology, the hospital aims to enhance health outcomes through rigorous research and evidence-based practices. Its commitment to high standards in clinical trial management ensures the integrity and reliability of its studies, contributing significantly to the global medical community.

Locations

New Taipei City, , Taiwan

Patients applied

0 patients applied

Trial Officials

Ying-Hsuan Tai, M.D., M.Sc.

Principal Investigator

Department of Anesthesiolgy, Shuang-Ho Hospital, Taipei Medical University, Taiwan

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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