A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
Launched by ELI LILLY AND COMPANY · May 18, 2020
Trial Information
Current as of July 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a medication called lasmiditan to see if it is safe and effective for children aged 6 to 17 who suffer from migraines. The researchers want to find out if this treatment can help manage migraine symptoms in young patients who have experienced at least two to eight moderate-to-severe migraine attacks each month for the past two months. To be eligible for the study, children must have a history of migraine for more than six months, be able to swallow a tablet, and weigh at least 15 kilograms (about 33 pounds).
The study will last up to 20 weeks and may involve around four visits to the research site. Participants will need to have stable migraine preventive medication for at least three months before joining the trial. It's important to note that children who are pregnant, nursing, or have serious health issues cannot participate. This study aims to improve treatment options for young people suffering from migraines, and everyone involved will be closely monitored to ensure their safety throughout the trial.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- * Participants must have a history of migraine with or without aura as defined by International Headache Society International Classification of Headache Disorders, 3rd edition (ICHD-3) (ICHD-3 2018) diagnostic criteria 1.1 or 1.2.1 and meets the following criteria:
- • History of migraine attacks for more than 6 months
- • Reports at least 2 and no more than 8 moderate-to-severe migraine attacks per month in the 2 months prior to screening visit
- • Duration of a typical untreated migraine attack (excluding sleep) is greater than or equal to 3 hours
- • Participant has not, by history, experienced satisfactory response with a previous migraine therapy, in the opinion of the investigator
- • Participant must be able to swallow a tablet
- • For participants taking migraine preventive medication, treatment regimen is stable and has been taken for at least 3 months prior to screening
- • Participants must weigh at least 15 kilograms (kg)
- Exclusion Criteria:
- • Participants must not be pregnant or nursing
- • Participants must not have any acute, serious, or unstable medical condition
- • Participants must not be actively suicidal or at significant risk for suicide, in the opinion of the investigator
About Eli Lilly And Company
Eli Lilly and Company is a global healthcare leader dedicated to creating innovative medicines that improve patient outcomes across a range of therapeutic areas, including diabetes, oncology, immunology, and neurodegenerative diseases. With a rich history of scientific research and a commitment to advancing healthcare, Lilly invests significantly in clinical trials to develop new treatments and enhance existing therapies. The company prioritizes patient safety and ethical standards in its clinical research, fostering collaboration with healthcare professionals and stakeholders to ensure the delivery of high-quality, evidence-based solutions that address unmet medical needs worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
East Lansing, Michigan, United States
Kansas City, Missouri, United States
New Orleans, Louisiana, United States
Madrid, , Spain
Corpus Christi, Texas, United States
Miami, Florida, United States
Phoenix, Arizona, United States
Cincinnati, Ohio, United States
Washington, District Of Columbia, United States
Rochester, New York, United States
Portland, Oregon, United States
Aurora, Colorado, United States
New Orleans, Louisiana, United States
Seattle, Washington, United States
Cincinnati, Ohio, United States
Gent, , Belgium
Fort Wayne, Indiana, United States
New Port Richey, Florida, United States
Lexington, Kentucky, United States
Tacoma, Washington, United States
West Palm Beach, Florida, United States
Bay City, Michigan, United States
Baltimore, Maryland, United States
Barcelona, , Spain
Barcelona, , Spain
Valencia, , Spain
Toms River, New Jersey, United States
Nishinomiya, Hyogo, Japan
Paris, , France
Paris, , France
New Port Richey, Florida, United States
Freiburg, , Germany
Sevilla, , Spain
Valladolid, , Spain
New Delhi, Delhi, India
West Des Moines, Iowa, United States
Shinjuku Ku, Tokyo, Japan
Madrid, , Spain
Barcelona, , Spain
New Delhi, , India
Lille, , France
Sabadell, Barcelona, Spain
Barcelona, , Spain
Hiroshima, , Japan
Chapel Hill, North Carolina, United States
Hoffman Estates, Illinois, United States
Nijmegen, Gelderland, Netherlands
Stockport, , United Kingdom
Bellevue, Washington, United States
Pune, Maharashtra, India
Brussels, , Belgium
Imperial, California, United States
Tucson, Arizona, United States
Roma, , Italy
Jacksonville, Florida, United States
Tampa, Florida, United States
Madrid, , Spain
Jette, Brussels, Belgium
Newburgh, Indiana, United States
Phoenix, Arizona, United States
Bellevue, Washington, United States
Colorado Springs, Colorado, United States
Smithfield, Pennsylvania, United States
London, , United Kingdom
Pompano Beach, Florida, United States
Honolulu, Hawaii, United States
Mangalore, Karnataka, India
West Palm Beach, Florida, United States
Nagpur, Maharashtra, India
New Delhi, Delhi, India
Gurgaon, Haryana, India
Stamford, Connecticut, United States
Indianapolis, Indiana, United States
Milano, , Italy
Hoffman Estates, Illinois, United States
Florence, , Italy
Roma, , Italy
Savannah, Georgia, United States
Kolkata, West Bengal, India
Ponce, , Puerto Rico
Constanta, , Romania
Gent, Oost Vlaanderen, Belgium
Savannah, Georgia, United States
Chandigarh, , India
Seattle, Washington, United States
Great Yarmouth, Norfolk, United Kingdom
Bochum, Nordrhein Westfalen, Germany
Kyoto, , Japan
Maitland, Florida, United States
Oklahoma City, Oklahoma, United States
Long Beach, California, United States
Cerritos, California, United States
Austin, Texas, United States
Waxahachie, Texas, United States
Ocoee, Florida, United States
Scottdale, Pennsylvania, United States
Jacksonville, Florida, United States
Meridian, Idaho, United States
Nishinomiya, Hyogo, Japan
Pozuelo De Alarcon, Madrid, Spain
Pensacola, Florida, United States
Bochum, Nordrhein Westfalen, Germany
Toulouse Cedex 9, , France
Guadalajara, Jalisco, Mexico
Scottsdale, Arizona, United States
Tampa, Florida, United States
Amiens Cedex 1, , France
Marseille Cedex 5, , France
Strasbourg, , France
Birmingham, Alabama, United States
Creteil, , France
Everett, Washington, United States
Miami, Florida, United States
Monroe, North Carolina, United States
Clermont Ferrand, , France
Bad Homburg, Hesse, Germany
East Greenwich, Rhode Island, United States
Miami, Florida, United States
Ahmedabad, Gujarat, India
Thane, Maharashtra, India
Gent, East Flanders, Belgium
Evansville, Indiana, United States
Roma, , Italy
Sarnia, Ontario, Canada
Seattle, Washington, United States
Long Beach, California, United States
Ontario, California, United States
Miami, Florida, United States
Lexington, Kentucky, United States
Waltham, Massachusetts, United States
Burnsville, Minnesota, United States
Kansas City, Missouri, United States
Houston, Texas, United States
Essen, Nordrhein Westfalen, Germany
New Delhi, Delhi, India
Napoli, Naples, Italy
Kobe, Hyogo, Japan
Nishinomiya, Hyogo, Japan
Sendai, Miyagi, Japan
Kochi, , Japan
Kyoto, , Japan
Osaka, , Japan
Tokyo, , Japan
Ciudad De Mexico, Federal District, Mexico
Guadalajara, Ja, Mexico
Aguascalientes, , Mexico
Chihuahua, , Mexico
Zwolle, Overijssel, Netherlands
Caguas, , Puerto Rico
Tampa, Florida, United States
Kagoshima, , Japan
Fargo, North Dakota, United States
Owensboro, Kentucky, United States
Bucuresti, , Romania
Stamford, Connecticut, United States
Monterrey, Nuevo León, Mexico
Saint Petersburg, Sankt Peterburg, Russian Federation
Bloomsbury, London, United Kingdom
Saint Petersburg, , Russian Federation
Newburgh, Indiana, United States
Methuen, Massachusetts, United States
Miami, Florida, United States
New Haven, Connecticut, United States
Austin, Texas, United States
Evansville, Indiana, United States
Huntington, West Virginia, United States
Vega Baja, , Puerto Rico
Esplugues De Llobregat, Barcelona [Barcelona], Spain
Nottingham, Nottinghamshire, United Kingdom
Scottsdale, Arizona, United States
Freiburg, Baden Württemberg, Germany
Austin, Texas, United States
Pensacola, Florida, United States
Little Rock, Arkansas, United States
Chicago, Illinois, United States
Bowling Green, Kentucky, United States
Springfield, Missouri, United States
Greenville, South Carolina, United States
Wichita, Kansas, United States
Dijon, , France
New Haven, Connecticut, United States
Huntsville, Alabama, United States
Cerritos, California, United States
Exeter, California, United States
Los Angeles, California, United States
San Diego, California, United States
North Palm Beach, Florida, United States
Tampa, Florida, United States
Winter Park, Florida, United States
Meridian, Idaho, United States
Chicago, Illinois, United States
New Orleans, Louisiana, United States
Lawrence, Massachusetts, United States
Worcester, Massachusetts, United States
Chapel Hill, North Carolina, United States
Statesville, North Carolina, United States
Winston Salem, North Carolina, United States
Cincinnati, Ohio, United States
Greenville, South Carolina, United States
Norfolk, Virginia, United States
Tacoma, Washington, United States
Grace Hollogne, Liege, Belgium
Genk, Limburg, Belgium
Mont De Marsan Cedex, , France
Sindelfingen, Baden Württemberg, Germany
Bochum, North Rhine Westphalia, Germany
Mumbai, Maharashtra, India
Jaipur, Rajasthan, India
Jaipur, Rajasthan, India
Pavia, , Italy
Varese, , Italy
Kiryu, Gunma, Japan
Higashiyamaku, Kyoto, Japan
Minato Ku, Tokyo, Japan
Kai, Yamanashi, Japan
Cuernavaca, Morelos, Mexico
Bucharest, Sector 4, Romania
Brasov, , Romania
Iasi, , Romania
Moscow, Moskva, Russian Federation
Moscow, , Russian Federation
Moscow, , Russian Federation
Novosibirsk, , Russian Federation
Saint Petersburg, , Russian Federation
Valladolid, Castilla Y Leon, Spain
Esplugues De Llobregat, , Spain
London, Greater London, United Kingdom
London, Greater London, United Kingdom
Great Yarmouth, Norfolk, United Kingdom
Glasgow, , United Kingdom
Nottingham, , United Kingdom
Clermont Ferrand, Puy De Dôme, France
Esplugues De Llobregat, , Spain
London, London, City Of, United Kingdom
Kingwood, West Virginia, United States
Thane, Maharashtra, India
Miami, Florida, United States
London, , United Kingdom
Ponce, , Puerto Rico
Union City, Georgia, United States
Jacksonville, Florida, United States
Brussels, Bruxelles Capitale, Région De, Belgium
Meridian, Idaho, United States
Burnsville, Minnesota, United States
Mexico City, Distrito Federal, Mexico
Monterrey, Nuevo León, Mexico
Statesville, North Carolina, United States
Constanta, Constanța, Romania
Gurugram, Haryana, India
Saint Nicolas, Wallonne, Région, Belgium
Dorado, , Puerto Rico
Marseille, Bouches Du Rhône, France
Lille, Nord Pas De Calais, France
Valencia, Valenciana, Comunitat, Spain
Norman, Oklahoma, United States
Houston, Texas, United States
Clermont Ferrand, , France
Ammon, Idaho, United States
Austin, Texas, United States
Nagpur, Maharashtra, India
Ridgeland, Mississippi, United States
Milano, Lombardia, Italy
Meridian, Idaho, United States
Strasbourg, Bas Rhin, France
Bad Homburg, Hessen, Germany
Minato, Tokyo, Japan
Barcelona, Barcelona [Barcelona], Spain
Kobe, Hyogo, Japan
Metairie, Louisiana, United States
Layton, Utah, United States
Rochester, New York, United States
Firenze, Toscana, Italy
Mont De Marsan, Landes, France
Amiens, Somme, France
Miami, Florida, United States
Fort Wayne, Indiana, United States
Genk, Limburg, Belgium
Strasbourg, Bas Rhin, France
Toulouse, Haute Garonne, France
Créteil, Val De Marne, France
Napoli, Campania, Italy
Varese, , Italy
Kiryu, Gunma, Japan
Mexico City, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
Aguascalientes, , Mexico
Vega Baja, , Puerto Rico
Bucharest, București, Romania
Bucharest, București, Romania
Iasi, Iași, Romania
Brașov, , Romania
Moscow, , Russian Federation
Sabadell, Barcelona [Barcelona], Spain
Madrid, , Spain
London, London, City Of, United Kingdom
Glagow, Scotland, United Kingdom
Jackson, Mississippi, United States
Créteil, Val De Marne, France
Nagpur, Maharashtra, India
Tucson, Arizona, United States
Essen, Nordrhein Westfalen, Germany
Fargo, North Dakota, India
Bari, Puglia, Italy
Constanta, , Romania
Kelowna, British Columbia, Canada
Kiryu, Gunma, Japan
Naperville, Illinois, United States
Bowling Green, Kentucky, United States
New Orleans, Louisiana, United States
Ridgeland, Mississippi, United States
Providence, Utah, United States
Cuernavaca, Morelos, Mexico
Worcester, Massachusetts, United States
Logan, Utah, United States
Logan, Utah, United States
Kagoshima, , Japan
Monterrey, , Mexico
Saint Nicolas, , Belgium
Bucharest, , Romania
Sabadell, , Spain
Patients applied
Trial Officials
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM
Study Director
Eli Lilly and Company
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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