Ovarian Morphology in Girls

Launched by CORNELL UNIVERSITY · Jun 5, 2020

Keywords

ClinConnect Summary

This clinical trial, titled "Ovarian Morphology in Girls," is studying how the ovaries in adolescent girls develop and function, particularly in relation to their menstrual cycles. Regular menstrual cycles are important for a girl’s health and can help identify any reproductive health issues early on, such as polycystic ovary syndrome (PCOS). By using a special imaging technique called 3D transabdominal ultrasound, researchers want to see if changes in the ovaries can predict whether a girl’s menstrual cycle will be normal or irregular. They are also interested in finding out if factors like diet or gut health affect this development.

To participate in this study, girls aged 9 to 17 who have started their menstrual periods within the last 11 months may be eligible. Specifically, girls with a family history of PCOS are being recruited at the University of Rochester. Participants will undergo imaging tests and may be asked about their diet and lifestyle. It’s important to note that girls who are currently pregnant, breastfeeding, or taking certain medications that affect reproductive health are not eligible. Overall, this study aims to improve understanding of how adolescent girls develop reproductively and to help identify any concerns early on.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female adolescents aged 9 to 17 years
• • Menarche within 11 months of the enrollment visit
• • University of Rochester site only: Family history of PCOS (i.e., mother or aunt)
• Exclusion Criteria:
• • Current or recent use of medications or supplements known or suspected to interfere with reproductive or metabolic function in the past 2 months (e.g., contraceptives, metformin, steroids, anti-seizure medications)
• • Untreated and/or unstable medical or mental health condition known or suspected to interfere with reproductive or metabolic function
• • Currently pregnant or breast feeding
• • History of ovarian surgery
• • Presence of significant acute or chronic illness which may interfere with study participation