Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma

Launched by FRENCH AFRICA PEDIATRIC ONCOLOGY GROUP · Jun 9, 2020

Keywords

ClinConnect Summary

This clinical trial is focused on improving the way children with retinoblastoma, a type of eye cancer, are treated in low-income countries in Africa. While many children in wealthier countries have a very high chance of surviving this disease, the goal of this study is to help children in other regions by promoting earlier diagnosis and providing a set of treatment guidelines. The researchers believe that by starting treatment sooner, they can improve outcomes for these young patients.

To participate in this trial, children must have specific types of retinoblastoma, such as cancer affecting one or both eyes but not spreading outside the eye area. Unfortunately, children with more advanced stages of the disease, where the cancer has spread, cannot join this study. Participants can expect to receive care based on the new treatment recommendations being tested, which may provide better chances for recovery. The trial is currently looking for eligible children to join and contribute to this important research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Unilateral intraocular Retinoblastoma (RB)
• • Unilateral extraocular intraorbital (RB)
• • Bilateral intraocular (RB)
• • bilateral intraocular (RB) on one side and extraocular but intraorbital on the other side.
• Exclusion Criteria:
• • Externalized tumor mass
• • massive extension to optic nerve up to optical channeltumor
• • intracranial extension leptomeninges
• • cerebral parenchyma
• • extension to regional lymph nodes and/or remote metastases.
• • cerebrospinal fluid involvement.
• • Trilateral RB
• • Incapacity to followed the whole treatement.