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Search / Trial NCT04427891

Characteristics of Abdominal Fluid in Patients With Diverticulitis Hinchey III or IV

Launched by SAHLGRENSKA UNIVERSITY HOSPITAL · Jun 9, 2020

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Perforated Diverticulitis Peritonitis Protein Changes Microbiota

ClinConnect Summary

This clinical trial is focused on understanding the characteristics of abdominal fluid in patients with a serious condition known as perforated diverticulitis, which can lead to life-threatening inflammation in the abdomen. The study aims to explore changes in tissue and bacteria in the gut that occur due to this condition. Researchers hope to learn more about why diverticulitis develops and how it can lead to perforation, which is when the intestinal wall breaks down.

If you are considering participating in this trial, you might be eligible if you have symptoms of perforated diverticulitis and need emergency surgery, or if you have acute diverticulitis but are not immediately undergoing surgery. Patients scheduled for elective surgery due to colorectal cancer can also join. Participants will undergo assessments to help researchers gather important information about their condition. It's essential to note that those who do not have surgery or decide to withdraw from the study will not be able to participate. This research could provide valuable insights that might improve future treatments for patients with diverticulitis.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Signs of perforated diverticulitis with peritonitis and decision to perform emergency surgery (Group I)
  • Signs of acute diverticulitis and no decision of emergency surgery (Group II)
  • Patients with colorectal cancer planned for elective surgery (Group III)
  • Exclusion Criteria:
  • No surgery performed (Group I and III)
  • Withdrawn consent (any group)

About Sahlgrenska University Hospital

Sahlgrenska University Hospital, a leading healthcare institution in Sweden, is at the forefront of clinical research and innovation. Affiliated with the University of Gothenburg, the hospital integrates advanced medical care with cutting-edge research, facilitating a collaborative environment for scientific exploration and clinical trials. With a commitment to improving patient outcomes, Sahlgrenska University Hospital focuses on a wide range of therapeutic areas, leveraging its multidisciplinary expertise to advance healthcare solutions. The institution is dedicated to fostering ethical research practices and ensuring the highest standards of patient safety and care in all clinical trials.

Locations

Gothenburg, Västra Götaland Region, Sweden

Gothenburg, , Sweden

Patients applied

0 patients applied

Trial Officials

Eva Haglind, MD,PhD

Principal Investigator

Sahlgrenska univesitetssjukhuset

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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